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Monday Night Football odds, picks, predictions from NFL model: This four-way football parlay returns 12-1

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Week 2 of the 2022 NFL schedule concludes with a Monday Night Football doubleheader. The Buffalo Bills (1-0), who convincingly defeated the reigning champion Los Angeles Rams 31-10 on the road within the 2022 NFL Kickoff Game, will play their home opener against the Tennessee Titans (0-1). Within the second contest, the Minnesota Vikings (1-0) will visit the Philadelphia Eagles (1-0) in an NFC showdown. 

Buffalo is favored by 10 points and Philadelphia is favored by 2.5 in the newest NFL odds from Caesars Sportsbook, but which teams must you back along with your NFL bets? Before you make any Week 2 Monday Night Football picks or NFL parlays, be sure you take a look at the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up greater than $7,500 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2022 NFL season on an incredible 139-98 run on top-rated NFL picks that dates back to the 2017 season.  

The model also ranked in the highest 10 on NFLPickWatch 4 of the past six years on straight-up NFL picks and beat greater than 94% of CBS Sports Football Pick’em players 4 times during that span. Anyone who has followed it’s way up.

Now, the model has locked in 4 confident NFL best bets for Monday Night Football. When you successfully parlay its picks, you would be an enormous payout of greater than 12-1. You may only see the model’s Monday Night Football picks at SportsLine

Top Monday Night Football picks

After simulating each games 10,000 times, the model is high on the Over (47.5) within the Titans vs. Bills matchup. Buffalo racked up 413 yards of total offense against the Rams in its season-opener and took control of the sport within the second half, outscoring the hosts 21-0 over the ultimate half-hour. Quarterback Josh Allen finished three passing yards shy of 300, but figured into all 4 of the Bills’ touchdowns, throwing for 3 while running for one more.

Wideout Gabe Davis (ankle) is questionable after recording 88 receiving yards and a TD versus Los Angeles, but Allen still has his top goal, Stefon Diggs, who had eight catches for 122 yards and a rating. Tennessee, which is coming off a 21-20 loss to the Latest York Giants, will likely be without Dontrell Hilliard (hamstring) after the running back had a pair of TD receptions in Week 1. Nevertheless, Derrick Henry has played well against Buffalo in his profession, running for a complete of six touchdowns while averaging 83.5 yards in 4 meetings. See which other NFL parlay picks to make here.

The best way to make Monday Night Football NFL parlays

The model also jumped on three other picks, including one on an underdog that wins in almost half of simulations. You may only see the model’s Monday Night Football best bets and parlay at SportsLine

What are the model’s top Monday Night Football picks? And which underdog wins almost 50% of the time? Visit SportsLine now to see the NFL best bets from a model on a 139-98 run on its top-rated picks, and discover.

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